Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773902 | 0.87 | ALDH1A1 (0.44) | ALDH1A1TSHRHPGDALOX15HSD17B10 | |
| SCHEMBL6771821 | 0.86 | TLR7 (0.47) | ALDH1A1TLR7TLR8NUDT1MEN1 | |
| SCHEMBL6768345 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TSHRTLR7TLR8HPGD | |
| SCHEMBL6774073 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRTLR7TLR8HPGD | |
| SCHEMBL6774879 | 0.81 | TLR7 (0.48) | TLR7TLR8HPGDKDM4ENUDT1 | |
| SCHEMBL6778860 | 0.81 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL6779679 | 0.81 | HPGD (0.46) | ALDH1A1TSHRHPGDALOX15HSD17B10 | |
| SCHEMBL6768601 | 0.81 | TLR7 (0.45) | TLR7TLR8NUDT1 | |
| SCHEMBL6094643 | 0.81 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL6773544 | 0.81 | TLR7 (0.51) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |