Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 4/20 | 0.41 |
| ▸ | EDNRB | P24530 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769669 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2MAPTHTTPOLBMEN1 | |
| SCHEMBL6217804 | 0.70 | HSPA1A (0.43) | EDNRAEDNRBSMN1; SMN2MAPTPTPN7 | |
| SCHEMBL6640242 | 0.64 | ALDH1A1 (0.51) | EDNRAEDNRBNPC1MAPTRAB9A | |
| SCHEMBL12488726 | 0.62 | EDNRA (0.62) | EDNRAEDNRBSMN1; SMN2NPC1MAPT | |
| SCHEMBL12686733 | 0.62 | EDNRA (0.62) | EDNRAEDNRBSMN1; SMN2NPC1MAPT | |
| SCHEMBL10013150 | 0.62 | HPGD (0.54) | EDNRAEDNRBNPC1RAB9APOLB | |
| SCHEMBL23342993 | 0.61 | ALDH1A1 (0.51) | EDNRAEDNRBSMN1; SMN2MAPTRAB9A | |
| SCHEMBL23297818 | 0.61 | ALDH1A1 (0.51) | EDNRAEDNRBSMN1; SMN2MAPTRAB9A | |
| SCHEMBL29542982 | 0.61 | ALDH1A1 (0.51) | EDNRAEDNRBSMN1; SMN2MAPTRAB9A | |
| SCHEMBL23297838 | 0.61 | ALDH1A1 (0.51) | EDNRAEDNRBSMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699877-B2 | TREATING PAIN, MIGRAINE, AND VARIOUS OTHER DISEASES | GRUENENTHAL GMBH (DE) | 2004-03-02 | — | — | US | disclosed |