Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 8/20 | 0.54 |
| ▸ | MMP2 | P08253 | 6/20 | 0.54 |
| ▸ | MMP9 | P14780 | 5/20 | 0.54 |
| ▸ | MMP3 | P08254 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742759 | 1.00 | ADAMTS4 (0.61) | ADAMTS4RAB9AMMP13MMP2MMP9 | |
| SCHEMBL6741519 | 0.87 | MMP2 (0.60) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6738036 | 0.87 | MMP2 (0.60) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6732456 | 0.85 | MMP13 (0.63) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6738197 | 0.85 | MMP13 (0.63) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6736475 | 0.84 | MMP2 (0.51) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6741407 | 0.83 | MMP13 (0.56) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6739709 | 0.83 | ADAMTS4 (0.56) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6733022 | 0.82 | MMP13 (0.57) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6736584 | 0.81 | MMP2 (0.67) | ADAMTS4MMP13MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696456-B1 | CARBOCYCLIC ACIDS AND SALTS SUCH AS (2S,3R)-3-ETHYLSULFANYL-2-(4'-FLUORO-BIPHENYL-4-SULFONYLAMINO)-3- PHENYLPROPIONIC ACID, USED AS METALLOENZYME ANTAGONISTS FOR THE PROPHYLAXIS OF DEGENERATIVE JOINT DISEASE AND AS WOUND HEALING AGENTS | THE PROCTER & GAMBLE COMPANY | 2004-02-24 | — | — | US | claimed |