Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783520 | 1.00 | CA1 (0.36) | CA1CA2CA12CA9NPC1 | |
| SCHEMBL22002104 | 0.83 | ACHE (0.31) | CA1CA2CA12CA9ACHE | |
| SCHEMBL6769668 | 0.82 | — | — | |
| SCHEMBL9393474 | 0.80 | CA1 (0.36) | CA1CA2CA12CA9NPC1 | |
| SCHEMBL5029811 | 0.77 | — | — | |
| SCHEMBL21266872 | 0.77 | — | — | |
| SCHEMBL13737389 | 0.75 | CA1 (0.33) | CA1CA2CA12CA9NPC1 | |
| SCHEMBL92328 | 0.75 | SHBG (0.36) | CA1CA2CA12CA9EPHX1 | |
| SCHEMBL105827 | 0.75 | SHBG (0.36) | CA1CA2CA12CA9EPHX1 | |
| SCHEMBL2811915 | 0.75 | ACHE (0.38) | CA1CA2CA12CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486499-A1 | Endo-2,3-epoxy-7-oxabicylco[2.2.1]heptane-endo-5-carboxylic acid derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6797832-B1 | Process for the production of 5-oxy-7-oxabicyclo [4.1.0] hept-3-ene-3-carboxylic acid esters | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1245569-A1 | PROCESS FOR THE PRODUCTION OF 5-OXY-7-OXABICYCLO- 4.1.0]HEPT-3-E NE-3-CARBOXYLIC ACID ESTERS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-4186185-A | Compositions comprising arylene substituted poly(orthoesters) containing useful agents | ALZA CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |
| US-4155740-A | SUSTAINED RELEASE | ALZA CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4136252-A | POLYETHERS, SUSTAINED RELEASE COATINGS | ALZA CORPORATION (US) | 1979-01-23 | — | — | US | disclosed |
| US-4119579-A | Polymeric orthoesters | ALZA CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-4066747-A | Polymeric orthoesters housing beneficial drug for controlled release therefrom | ALZA CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |