Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768203 | 0.88 | GHSR (0.43) | CA1CA2CA12CA9GHSR | |
| SCHEMBL6492295 | 0.86 | GHSR (0.45) | SMN1; SMN2CA1CA2CA12CA9 | |
| SCHEMBL6497769 | 0.85 | CA1 (0.48) | CA1CA2PTGS2EGFRCA12 | |
| SCHEMBL6491807 | 0.85 | GHSR (0.46) | CA1CA2PTGS2CA12CA9 | |
| SCHEMBL6495487 | 0.80 | MAOB (0.49) | PKMEGFRCA12CA9AHR | |
| SCHEMBL6492603 | 0.80 | MAPT (0.53) | SMN1; SMN2CA1CA2CA12CA9 | |
| SCHEMBL6482868 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2EGFRAHRGSK3B | |
| SCHEMBL6493823 | 0.77 | EGFR (0.50) | SMN1; SMN2PKMEGFRAHR | |
| SCHEMBL6481651 | 0.76 | EGFR (0.43) | SMN1; SMN2CNR1EGFR | |
| SCHEMBL6765296 | 0.75 | DHFR (0.49) | SMN1; SMN2CA1CA2CNR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800656-B2 | Tricyclic compounds and method of treating herpes virus | WARNER LAMBERT COMPANY | 2004-10-05 | — | — | US | claimed |