Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151288 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6772118 | 0.82 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL8785066 | 0.80 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL7939644 | 0.80 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL6766267 | 0.80 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL6777322 | 0.80 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL6771045 | 0.79 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL8350252 | 0.78 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6772729 | 0.78 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL6777867 | 0.78 | EDNRA (0.86) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | claimed |
| EP-0569193-B1 | N-isoxazole-phenylsulfonamide derivatives and their use as endothelin antagonists | SQUIBB & SONS INC (US) | 1997-02-26 | — | — | EP | claimed |
| EP-0569193-A1 | N-isoxazole-phenylsulfonamide derivatives and their use as endothelin antagonists | E.R. SQUIBB & SONS, INC. (US) | 1993-11-10 | — | — | EP | claimed |
| US-6673824-B1 | HYPOTENSIVE AGENTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0569193-B1 | N-isoxazole-phenylsulfonamide derivatives and their use as endothelin antagonists | SQUIBB & SONS INC (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0569193-A1 | N-isoxazole-phenylsulfonamide derivatives and their use as endothelin antagonists | E.R. SQUIBB & SONS, INC. (US) | 1993-11-10 | — | — | EP | disclosed |