Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.58 |
| ▸ | GABRD | O14764 | 20/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.58 |
| ▸ | GABRE | P78334 | 20/20 | 0.58 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.58 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.58 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.58 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157029 | 0.87 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12666119 | 0.86 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6264775 | 0.85 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14724035 | 0.85 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055611 | 0.85 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1157032 | 0.85 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055669 | 0.85 | GABRP (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15406 | 0.85 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2837760 | 0.84 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9430248 | 0.84 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791046-B2 | Crystalline modification of fipronil | BASF SE (DE) | 2014-07-29 | — | — | US | disclosed |
| US-8383664-B2 | Crystalline modification of fipronil | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |
| WO-2012164571-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2012-12-06 | — | — | WO | disclosed |
| US-8323904-B2 | Kit for measurement of termite insecticide active ingredient by immunoassay method | BAYER CROPSCIENCE AG (DE) | 2012-12-04 | — | — | US | disclosed |
| US-8188136-B2 | Crystalline modification of fipronil | BASF SE (DE) | 2012-05-29 | — | — | US | disclosed |
| US-8097603-B2 | Compositions for controlling parasites on animals | BAYER ANIMAL HEALTH GMBH (DE) | 2012-01-17 | — | — | US | disclosed |
| US-8063092-B2 | Crystalline modification of fipronil | BASF SE (DE) | 2011-11-22 | — | — | US | disclosed |
| WO-2011089616-A1 | PROCESS FOR MANUFACTURING 5-AMINO-1-(2, 6-DICHLORO-4-TRIFLU OROMETHYL PHENYL)-3-CYANO-4-TRIFLUOROMETHYL SULPHINYL PYRAZOLE | GHARDA KEKI HORMUSJI (IN) | 2011-07-28 | — | — | WO | disclosed |
| US-7939565-B2 | N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide and one or more of tebufenozide, deltamethrin,ethiprole, fipronil, indoxacarb, emamectin-benzoate, abamectin, spinosad | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | disclosed |
| EP-1553829-B1 | ACTIVE SUBSTANCE COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2011-03-30 | — | — | EP | disclosed |
| US-20100105752-A1 | Crystalline Modification of Fipronil | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100081698-A1 | Crystalline Modification of Fipronil | BASF SE (DE) | 2010-04-01 | — | — | US | disclosed |
| US-20100047927-A1 | KIT FOR MEASUREMENT OF TERMITE INSECTICIDE ACTIVE INGREDIENT BY IMMUNOASSAY METHOD | BAYER CROPSCIENCE K.K. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20100041552-A1 | Crystalline Modification of Fipronil | BASF SE (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100041727-A1 | Crystalline Modification of Fipronil | BASF SE (DE) | 2010-02-18 | — | — | US | disclosed |
| EP-1624756-B1 | AGENTS FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2009-06-24 | — | — | EP | disclosed |
| US-20080214634-A1 | Active substance combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | US | disclosed |
| US-7288572-B2 | Active substance combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-20070015835-A1 | Active substance combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041552-A1 | Crystalline Modification of Fipronil | FIP1L1, PTMS, FIBP | GABRP 741/4885GABRD 3460/4885GABRA1 2189/4885 |
| US-20080214634-A1 | Active substance combinations having insecticidal and acaricidal properties | ACHE, DDT, AADAC | GABRP 447/4885GABRD 2472/4885GABRA1 1753/4885 |
| US-20100105752-A1 | Crystalline Modification of Fipronil | FIP1L1, PTMS, FIBP | GABRP 741/4885GABRD 3460/4885GABRA1 2189/4885 |
| US-20100041727-A1 | Crystalline Modification of Fipronil | FIP1L1, PTMS, FIBP | GABRP 731/4885GABRD 3565/4885GABRA1 2192/4885 |
| US-20070015835-A1 | Active substance combinations having insecticidal and acaricidal properties | ACHE, DDT, AADAC | GABRP 447/4885GABRD 2472/4885GABRA1 1753/4885 |
| US-20100081698-A1 | Crystalline Modification of Fipronil | FIP1L1, PTMS, FIBP | GABRP 741/4885GABRD 3460/4885GABRA1 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.