Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.64 |
| ▸ | GABRD | O14764 | 20/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.64 |
| ▸ | GABRE | P78334 | 20/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.64 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.64 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.64 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834347 | 0.93 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13389377 | 0.90 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055611 | 0.90 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055669 | 0.90 | GABRP (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14724035 | 0.90 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6264775 | 0.90 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1157032 | 0.90 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15406 | 0.90 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2837760 | 0.89 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9430248 | 0.89 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881848-B2 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | BASF Agro B.V. Arnhem (NL), Wädenswil-Branch (CH) | 2005-04-19 | — | — | US | claimed |
| US-20040034234-A1 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 2004-02-19 | — | — | US | claimed |
| WO-2023279671-A1 | METHOD FOR SYNTHESIZING FIPRONIL INTERMEDIATE | 浙江海正药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |
| US-8629287-B2 | Process for the sulfinylation of a pyrazole derivative | BASF SE (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120309806-A1 | Process for the Sulfinylation of a Pyrazole Derivative | BASF SE (DE) | 2012-12-06 | — | — | US | disclosed |
| US-8263783-B2 | Process for the sulfinylation of a pyrazole derivative | BASF SE (DE) | 2012-09-11 | — | — | US | disclosed |
| US-20110034530-A1 | PROCESS FOR THE PREPARATION OF FIPRONIL AND ANALOGUES THEREOF | VETOQUINOL (FR) | 2011-02-10 | — | — | US | disclosed |
| EP-2231616-A1 | PROCESS FOR THE PREPARATION OF FIPRONIL AND ANALOGUES THEREOF | Vétoquinol (FR) | 2010-09-29 | — | — | EP | disclosed |
| US-20100137395-A1 | Process for the Sulfinylation of a Pyrazole Derivative | BASF SE (DE) | 2010-06-03 | — | — | US | disclosed |
| US-20100093822-A1 | Process for the Sulfinylation of a Pyrazole Derivative | BASF SE (DE) | 2010-04-15 | — | — | US | disclosed |
| US-20100004307-A1 | Process for the Sulfinylation of a Pyrazole Derivative | BASF SE (DE) | 2010-01-07 | — | — | US | disclosed |
| WO-2009077853-A1 | PROCESS FOR THE PREPARATION OF FIPRONIL AND ANALOGUES THEREOF | VÉTOQUINOL (FR) | 2009-06-25 | — | — | WO | disclosed |
| US-6881848-B2 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | BASF Agro B.V. Arnhem (NL), Wädenswil-Branch (CH) | 2005-04-19 | — | — | US | disclosed |
| US-20040034234-A1 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 2004-02-19 | — | — | US | disclosed |
| US-6638956-B2 | Pesticidal 1-arylpyrazoles | RHONE-POULENC, INC. | 2003-10-28 | — | — | US | disclosed |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2003-07-31 | — | — | US | disclosed |
| CN-1032201-C | Process for preparing perhaloalkylthioethers | RHONE POULENC AGROCHIMIE (FR) | 1996-07-03 | — | — | CN | disclosed |
| US-5283337-A | Reacting reducing agent, disulfide, perhaloalkyl halide | RHONE-POULENC AGROCHIMIE (FR) | 1994-02-01 | — | — | US | disclosed |
| US-5082945-A | Reducing agent, perfluoroalkyl halide, disulfide | RHONE-POULENC AGROCHIMIE (FR) | 1992-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093822-A1 | Process for the Sulfinylation of a Pyrazole Derivative | STS, SFXN3, ARSA | GABRP 1803/4885GABRD 3654/4885GABRA1 2709/4885 |
| US-20110034530-A1 | PROCESS FOR THE PREPARATION OF FIPRONIL AND ANALOGUES THEREOF | NOX5, CYP3A5, PPOX | GABRP 1686/4885GABRD 3466/4885GABRA1 2696/4885 |
| US-20120309806-A1 | Process for the Sulfinylation of a Pyrazole Derivative | STS, SULT1A1, SULT2A1 | GABRP 1616/4885GABRD 2122/4885GABRA1 1744/4885 |
| US-20040034234-A1 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | CYP2F1, CYP4F2, F12 | GABRP 475/4885GABRD 1365/4885GABRA1 282/4885 |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | GABRP 1208/4885GABRD 2403/4885GABRA1 1171/4885 |
| US-20100137395-A1 | Process for the Sulfinylation of a Pyrazole Derivative | STS, SULT1A1, SULT2A1 | GABRP 1575/4885GABRD 1998/4885GABRA1 1661/4885 |
| US-20100004307-A1 | Process for the Sulfinylation of a Pyrazole Derivative | STS, SFXN3, ARSA | GABRP 1891/4885GABRD 3123/4885GABRA1 2148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.