Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 1.00 |
| ▸ | CCR5 | P51681 | 3/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770148 | 0.84 | CCR2 (0.81) | CCR2ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL5626457 | 0.81 | ALDH1A1 (0.74) | CCR2ALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL3156886 | 0.81 | KDM4E (0.73) | CCR2ALDH1A1KDM4ESMN1; SMN2HRH3 | |
| SCHEMBL11848227 | 0.80 | CCR2 (0.73) | CCR2KDM4ESIGMAR1LMNA | |
| SCHEMBL6418223 | 0.79 | CCR2 (0.65) | CCR2CCR5HTR1ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL11838606 | 0.78 | CCR2 (0.71) | CCR2KDM4ESIGMAR1LMNA | |
| SCHEMBL2206628 | 0.78 | KDM4E (0.73) | CCR2ALDH1A1KDM4ESMN1; SMN2HRH3 | |
| SCHEMBL6768880 | 0.78 | CCR2 (0.64) | CCR2CCR5GAA | |
| SCHEMBL4483824 | 0.78 | KDM4E (0.70) | CCR2HTR1AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4475769 | 0.78 | KDM4E (0.70) | CCR2HTR1AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9309877-A | — | — | None | — | — | JP | disclosed |
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| JP-H09309877-A | CYCLIC DIAMINE DERIVATIVE AND ITS PRODUCTION AND USE | TEIJIN LTD | 1997-12-02 | — | — | JP | disclosed |