Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612560 | 0.90 | SLC1A3 (0.40) | MMP1MMP2MMP9MMP8PKLR | |
| SCHEMBL6610307 | 0.84 | ALDH1A1 (0.38) | MMP1MMP2MMP9MMP8SLC1A3 | |
| SCHEMBL6777805 | 0.83 | ALDH1A1 (0.39) | CASP1CNR2 | |
| SCHEMBL6613207 | 0.81 | CASP1 (0.42) | MMP1MMP2MMP9MMP8CASP1 | |
| SCHEMBL6613382 | 0.80 | CASP3 (0.47) | CASP1 | |
| SCHEMBL6609343 | 0.78 | CASP1 (0.38) | MMP1MMP2MMP9MMP8CASP1 | |
| SCHEMBL6611623 | 0.78 | TSHR (0.40) | F2MAPT | |
| SCHEMBL6609360 | 0.77 | ALDH1A1 (0.39) | MAPT | |
| SCHEMBL6611153 | 0.75 | ALDH1A1 (0.41) | MMP1MMP2MMP9CASP1CNR2 | |
| SCHEMBL6776222 | 0.75 | ALDH1A1 (0.41) | MMP1MMP2MMP9CASP1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747050-B1 | INHIBITING THE ACTIVITY OF CASPASES, PREVENTING INFLAMMATION AND APOPTOSIS | LG CHEM INVESTMENT LTD. (KR) | 2004-06-08 | — | — | US | disclosed |