Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770560 | 0.91 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL6767692 | 0.82 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL6770780 | 0.81 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL7212795 | 0.80 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL6640611 | 0.79 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7550896 | 0.79 | EDNRA (0.63) | EDNRAEDNRB | |
| SCHEMBL6773708 | 0.78 | EDNRA (0.82) | EDNRAEDNRB | |
| SCHEMBL6766562 | 0.76 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL6772509 | 0.76 | EDNRB (0.72) | EDNRAEDNRB | |
| SCHEMBL7856709 | 0.74 | EDNRB (0.81) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673824-B1 | HYPOTENSIVE AGENTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | disclosed |
| US-5514696-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 1996-05-07 | — | — | US | disclosed |