Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766562 | 0.79 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL6771340 | 0.79 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL6770783 | 0.78 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6770560 | 0.78 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL6772509 | 0.76 | EDNRB (0.72) | EDNRAEDNRB | |
| SCHEMBL6777975 | 0.75 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL7552444 | 0.72 | ALDH1A1 (0.48) | EDNRAEDNRB | |
| SCHEMBL6770437 | 0.72 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL7947798 | 0.72 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL6772995 | 0.71 | EDNRA (0.76) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237888-A2 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2002-09-11 | — | — | EP | claimed |
| WO-2001044239-A2 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB CO. (US) | 2001-06-21 | — | — | WO | claimed |