Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770780 | 0.90 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL6771340 | 0.82 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL6771908 | 0.82 | EDNRB (0.72) | EDNRAEDNRB | |
| SCHEMBL6771743 | 0.81 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL6640611 | 0.77 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6771110 | 0.72 | L3MBTL1 (0.38) | — | |
| SCHEMBL6772789 | 0.71 | CA12 (0.51) | — | |
| SCHEMBL6771731 | 0.70 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL27466694 | 0.70 | EDNRA (0.74) | EDNRAEDNRB | |
| SCHEMBL7716850 | 0.69 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673824-B1 | HYPOTENSIVE AGENTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | disclosed |
| US-5514696-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 1996-05-07 | — | — | US | disclosed |