SCHEMBL677174

SCHEMBL677174

COc1ncc(Cl)c(C)c1C=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 7/20 0.35
DAO P14920 1/20 0.34
NFE2L2 Q16236 2/20 0.33
LRRK2 Q5S007 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
RORC P51449 1/20 0.31
PLAU P00749 1/20 0.31
GAA P10253 1/20 0.31
S100A9 P06702 1/20 0.30
KCNJ5 P48544 1/20 0.30
KCNJ3 P48549 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
AOX1 Q06278 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18299236 0.80 CCR4 (0.36) CCR4NFE2L2LRRK2ALDH1A1MEN1
SCHEMBL28608990 0.78 AKR1B1 (0.31) LRRK2
SCHEMBL15004234 0.77 DAO (0.36) CCR4DAOLRRK2MEN1KMT2A
SCHEMBL27642261 0.76 DAO (0.33) CCR4DAO
SCHEMBL676596 0.76 DAO (0.33) CCR4DAORORCPLAULMNA
SCHEMBL29955376 0.76 DAO (0.37) DAOALDH1A1MEN1KMT2ATDP1
SCHEMBL5396028 0.75 ALDH1A1 (0.36) CCR4NFE2L2ALDH1A1MEN1KMT2A
SCHEMBL12140992 0.75 PLAU (0.43) CCR4DAOMEN1KMT2ARORC
SCHEMBL27973006 0.73 DAO (0.34) CCR4DAOLRRK2ALDH1A1KMT2A
SCHEMBL438652 0.73 NFE2L2 (0.42) CCR4NFE2L2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112441967-B Preparation method of methoxybenzene cry bacterial intermediate 南北兄弟药业投资有限公司 2024-10-29 CN disclosed
CN-112441967-B Preparation method of methoxybenzene cry bacterial intermediate 南北兄弟药业投资有限公司 2024-10-29 CN disclosed
CN-116640092-A Benzyloxy substituted bipyridine methanone compound and application thereof 南北兄弟药业投资有限公司 2023-08-25 CN disclosed
CN-112441967-A Preparation method of methoxybenzene cry bacterial intermediate 南北兄弟药业投资有限公司 2021-03-05 CN disclosed
CN-112441967-A Preparation method of methoxybenzene cry bacterial intermediate 南北兄弟药业投资有限公司 2021-03-05 CN disclosed
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA (JP) 2017-07-06 US disclosed
US-9655362-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-05-23 US disclosed
EP-1679003-B1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA (JP) 2015-04-15 EP disclosed
US-8653277-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-02-18 US disclosed
US-8653113-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-02-18 US disclosed
US-8609150-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-12-17 US disclosed
US-20120135088-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-05-31 US disclosed
US-20110280959-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-11-17 US disclosed
EP-2338335-A1 Preparation of fungicidal benzoylpyridine derivatives ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-06-29 EP disclosed
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-10-01 US disclosed
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-08-31 US disclosed
EP-1679003-A1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CBR1, CNPY2 CCR4 1611/4885DAO 9/4885NFE2L2 2145/4885
US-20120135088-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CNPY2, PAH CCR4 1182/4885DAO 14/4885NFE2L2 1958/4885
US-20110280959-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CNPY2, PAH CCR4 1182/4885DAO 14/4885NFE2L2 1958/4885
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases CBR3, CNPY2, PAH CCR4 1182/4885DAO 14/4885NFE2L2 1958/4885
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CNPY2, PAH CCR4 1182/4885DAO 14/4885NFE2L2 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.