Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491757 | 0.90 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2AHTTMAP4K4 | |
| SCHEMBL9492874 | 0.88 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2AHTTF2 | |
| SCHEMBL959837 | 0.86 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9496948 | 0.85 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2ANPC1HTT | |
| SCHEMBL958339 | 0.85 | MEN1 (0.51) | L3MBTL1MEN1KMT2AHTTHAO1 | |
| SCHEMBL2144034 | 0.82 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9271136 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2AHTTLTA4H | |
| SCHEMBL16695498 | 0.81 | MEN1 (0.51) | L3MBTL1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL11687023 | 0.81 | MAOA (0.48) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9494460 | 0.81 | L3MBTL1 (0.56) | L3MBTL1MEN1KMT2AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787551-B2 | ORAL ADMINISTRATION; TREATING INSULIN RESISTANCE USING A NEW MECHANISM TO LOWER BLOOD SUGAR LEVEL BY INCREASING PHYSIOLOG-ICAL EFFECTS OF INSULIN ON TARGET CELLS (MUSCLE, ADIPOCYTES, LIVER); ALSO STRONGER ANTILIPIDEMIC THAN ROSIGLITAZONE | CHONG KUN DANG PHARMACEUTICAL CORPORATION (KR) | 2004-09-07 | — | — | US | disclosed |
| US-20040122031-A1 | Thiazolidinedione and pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-06-24 | — | — | US | disclosed |
| US-4499275-A | PESTICIDES; INSECTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| US-4393213-A | Process for producing 6-phenoxypicolinic aldehydes | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4132784-A | (Substituted pyridyl)phenoxy phosphorus compounds and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4132783-A | (Substituted pyridyl)phenoxy phosphorus compounds and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4080443-A | (Substituted pyridyl)phenoxy phosphorous compounds and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122031-A1 | Thiazolidinedione and pharmaceutical composition comprising the same | GLP1R, PPARD, SLC5A1 | L3MBTL1 4518/4885MEN1 3913/4885KMT2A 3993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.