SCHEMBL9496948

SCHEMBL9496948

Clc1cccc(Oc2ccc(-c3ccc(Oc4cccc(Cl)n4)cc3)cc2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.49
F2 P00734 4/20 0.44
F10 P00742 4/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
ST14 Q9Y5Y6 1/20 0.44
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
HAO1 Q9UJM8 2/20 0.42
PTGS2 P35354 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
LTA4H P09960 1/20 0.40
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
P2RX3 P56373 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9491757 0.94 L3MBTL1 (0.53) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL9492874 0.92 L3MBTL1 (0.51) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL2905358 0.91 L3MBTL1 (0.47) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL958339 0.88 MEN1 (0.51) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL2144034 0.86 L3MBTL1 (0.54) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL16695498 0.85 MEN1 (0.51) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL9271136 0.85 L3MBTL1 (0.50) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL11687023 0.85 MAOA (0.48) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL6772010 0.85 L3MBTL1 (0.54) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL9494460 0.84 L3MBTL1 (0.56) L3MBTL1F2F10PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255778-B1 THERMOPLASTIC AROMATIC POLYETHER-PYRIDINES AND PROCESS FOR PREPARING SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-03 EP disclosed
US-4803258-A FROM DIHALOGENOPYRIDINE AND DIOL, MOLDING MATERIALS, FILMS, WIRE COATING MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-07 US disclosed