Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 3/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138044 | 0.81 | GRIA4 (0.52) | GRIA4GRIA2ALDH1A1HSD17B10TSHR | |
| SCHEMBL14549321 | 0.78 | GPR35 (0.42) | GRIA4ALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL8282826 | 0.78 | GRIA4 (0.82) | GRIA4GRIA2KMT2A | |
| SCHEMBL1313857 | 0.75 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TSHRMAPK1GAA | |
| SCHEMBL5728897 | 0.73 | GRIA4 (0.75) | GRIA4GRIA2KMT2A | |
| SCHEMBL3128683 | 0.73 | L3MBTL1 (0.56) | ALDH1A1HSD17B10TSHRMAPK1GAA | |
| SCHEMBL5728066 | 0.72 | GRIA4 (0.73) | GRIA4GRIA2KMT2A | |
| SCHEMBL2550483 | 0.72 | ALDH1A1 (0.41) | GRIA4GRIA2ALDH1A1HSD17B10TSHR | |
| SCHEMBL3128688 | 0.71 | L3MBTL1 (0.50) | GRIA4GRIA2ALDH1A1RXFP1HPGD | |
| SCHEMBL8281925 | 0.70 | GRIA4 (0.70) | GRIA4GRIA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683055-B1 | GUANIDINE OR AMIDINE TERMINED PEPTIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |