Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728511 | 0.87 | ESR1 (0.42) | MEN1KMT2ANPC1ERN1ALDH1A1 | |
| SCHEMBL6772440 | 0.83 | NPC1 (0.46) | MEN1KMT2ANPC1HSP90AA1PTGS2 | |
| SCHEMBL5731027 | 0.79 | PTGS2 (0.60) | HSP90AA1PTGS2PTGS1PDE3AESR1 | |
| SCHEMBL5730530 | 0.79 | PTGS2 (0.60) | HSP90AA1PTGS2PTGS1PDE3AESR1 | |
| SCHEMBL7662656 | 0.77 | ALDH1A1 (0.33) | MEN1KMT2AHSP90AA1ALDH1A1HPGD | |
| SCHEMBL7846866 | 0.72 | ERN1 (0.41) | MEN1KMT2APTGS2ERN1ALDH1A1 | |
| SCHEMBL5729727 | 0.72 | HSP90AA1 (0.48) | MEN1KMT2ANPC1HSP90AA1PTGS1 | |
| SCHEMBL5729672 | 0.71 | PTGS2 (0.70) | PTGS2PTGS1PDE3A | |
| SCHEMBL7855239 | 0.70 | ALDH1A1 (0.39) | MEN1KMT2ANPC1HSP90AA1PTGS2 | |
| SCHEMBL5729553 | 0.69 | ESR1 (0.53) | MEN1KMT2APTGS2PTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743815-B2 | OSTEOPOROSIS; ENDOMETRIOSIS; ALZHEIMER'S DISEASE | CHIRON CORPORATION | 2004-06-01 | — | — | US | claimed |