Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359069 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL9412370 | 0.67 | MAPT (0.33) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL10925032 | 0.65 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL14751602 | 0.65 | CFTR (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL6250597 | 0.65 | SIGMAR1 (0.38) | ALDH1A1ALOX12SIGMAR1CFTRGOPC | |
| SCHEMBL21239628 | 0.64 | NPC1 (0.33) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL31193327 | 0.62 | — | — | |
| SCHEMBL21306498 | 0.62 | MEN1 (0.45) | ALDH1A1KMT2APOLBMEN1LMNA | |
| SCHEMBL11506718 | 0.61 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL3135606 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863391-B2 | Organopolysiloxane and curable silicone composition that contains aforementioned organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-01-04 | — | — | US | disclosed |
| US-20080207848-A1 | Organopolysiloxane and Curable Silicone Composition that Contains Aforementioned Organopolysiloxane | DOW CORNING TORAY CO., LTD. (JP) | 2008-08-28 | — | — | US | disclosed |