SCHEMBL6772633

SCHEMBL6772633

CCCC[Sn](CCCC)(CCCC)c1sc2cncn2c1C(C)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 19/20 0.33
TDO2 P48775 19/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636941 0.80 IDO1 (0.33) IDO1TDO2
SCHEMBL6894660 0.76 IDO1 (0.34) IDO1TDO2
SCHEMBL6895518 0.73 IDO1 (0.39) IDO1TDO2
SCHEMBL6888033 0.72
SCHEMBL7629241 0.71 IDO1 (0.38) IDO1TDO2
SCHEMBL6887026 0.71
SCHEMBL7630451 0.67 TBXAS1 (0.33)
SCHEMBL7493445 0.64
SCHEMBL6890828 0.64
SCHEMBL6891554 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6825187-B2 CARBAPENEM DERIVATIVES SUBSTITUTED AT THE 2-POSITION WITH A SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP; USE AGAINST ANTIBIOTIC RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA, ENTEROCOCCI AND INFLUENZA VIRUS MEIJI SEIKA KAISHA, LTD. (JP) 2004-11-30 US disclosed