SCHEMBL7629241

SCHEMBL7629241

CCCC[Sn](CCCC)(CCCC)c1c(C)sc2cncn12

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.38
TDO2 P48775 17/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636941 0.79 IDO1 (0.33) IDO1TDO2
SCHEMBL6894660 0.73 IDO1 (0.34) IDO1TDO2
SCHEMBL7630451 0.72 TBXAS1 (0.33)
SCHEMBL6772633 0.71 IDO1 (0.33) IDO1TDO2
SCHEMBL6895518 0.70 IDO1 (0.39) IDO1TDO2
SCHEMBL7493445 0.69
SCHEMBL7634272 0.68 IDO1 (0.49) IDO1TDO2
SCHEMBL22188406 0.65 IDO1 (0.46) IDO1TDO2
SCHEMBL7490921 0.65 IDO1 (0.47) IDO1TDO2
SCHEMBL7495796 0.65 IDO1 (0.43) IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1022279-B1 NEW CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA (JP) 2002-09-04 EP disclosed
US-6310056-B1 2-SUBSTITUTED WITH A IMIDAZO(5,1-B)THIAZOLE GROUP; TREATING INFECTIONS, INCLUDING ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS MEIJI SEIKA KAISHA, LTD. (JP) 2001-10-30 US disclosed
EP-1022279-A1 NEW CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 2000-07-26 EP disclosed