Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 19/20 | 0.33 |
| ▸ | TDO2 | P48775 | 19/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894660 | 0.82 | IDO1 (0.34) | IDO1TDO2TBXAS1 | |
| SCHEMBL6772633 | 0.80 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL7629241 | 0.79 | IDO1 (0.38) | IDO1TDO2 | |
| SCHEMBL6895518 | 0.79 | IDO1 (0.39) | IDO1TDO2TBXAS1 | |
| SCHEMBL6888033 | 0.74 | — | — | |
| SCHEMBL7630451 | 0.72 | TBXAS1 (0.33) | TBXAS1 | |
| SCHEMBL6766956 | 0.70 | CYP1A2 (0.32) | — | |
| SCHEMBL7493445 | 0.69 | — | — | |
| SCHEMBL7634272 | 0.68 | IDO1 (0.49) | IDO1TDO2 | |
| SCHEMBL7629274 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022279-B1 | NEW CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6310056-B1 | 2-SUBSTITUTED WITH A IMIDAZO(5,1-B)THIAZOLE GROUP; TREATING INFECTIONS, INCLUDING ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1022279-A1 | NEW CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |
| EP-1000064-A1 | COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999001455-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-01-14 | — | — | WO | disclosed |