Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776588 | 0.88 | EPHX2 (0.37) | BACE1CTSDTLR7TLR8NUDT1 | |
| SCHEMBL6773457 | 0.87 | L3MBTL1 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6773840 | 0.87 | TLR7 (0.37) | HSP90AA1HSP90AB1TLR7TLR8NUDT1 | |
| SCHEMBL6093363 | 0.86 | TLR7 (0.36) | HSP90AA1HSP90AB1TLR7TLR8NUDT1 | |
| SCHEMBL6768386 | 0.85 | TLR7 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6777973 | 0.84 | TLR7 (0.37) | TLR7TLR8NUDT1 | |
| SCHEMBL6774067 | 0.84 | ALDH1A1 (0.39) | HSP90AA1HSP90AB1TLR7TLR8NUDT1 | |
| SCHEMBL6288804 | 0.84 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6772831 | 0.84 | FAAH (0.38) | NPY1RTLR7TLR8NUDT1 | |
| SCHEMBL6778341 | 0.84 | TLR7 (0.35) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |