Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768462 | 0.94 | TLR7 (0.38) | TLR7TLR8KMT2ASMN1; SMN2 | |
| SCHEMBL6775775 | 0.89 | EPHX1 (0.37) | TLR7TLR8KMT2A | |
| SCHEMBL6768601 | 0.86 | TLR7 (0.45) | TLR7TLR8 | |
| SCHEMBL6772471 | 0.83 | HPGD (0.46) | TLR7KMT2ASMN1; SMN2 | |
| SCHEMBL6774292 | 0.81 | ALDH1A1 (0.47) | TLR7KMT2A | |
| SCHEMBL6773171 | 0.80 | TSHR (0.38) | KMT2ASMN1; SMN2 | |
| SCHEMBL6776898 | 0.80 | EPHX1 (0.37) | TLR7SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6820241 | 0.78 | CSNK2A1 (0.37) | TLR7KMT2A | |
| SCHEMBL6721772 | 0.78 | CSNK2A1 (0.37) | TLR7KMT2A | |
| SCHEMBL6778418 | 0.78 | TLR7 (0.39) | TLR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |