Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777224 | 0.95 | EPHX1 (0.37) | EPHX1TLR7TLR8MAPTKDM4E | |
| SCHEMBL6773502 | 0.89 | TLR7 (0.37) | TLR7TLR8KMT2A | |
| SCHEMBL6094589 | 0.87 | DYRK1A (0.37) | TLR7KDM4E | |
| SCHEMBL6776898 | 0.86 | EPHX1 (0.37) | EPHX1TLR7MAPTKDM4ETDP1 | |
| SCHEMBL6778701 | 0.85 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6097539 | 0.84 | KMT2A (0.36) | TLR7GAARECQLKMT2ACYP3A4 | |
| SCHEMBL6772950 | 0.83 | FAAH (0.53) | EPHX1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL6768462 | 0.83 | TLR7 (0.38) | TLR7TLR8KMT2AHSD17B10 | |
| SCHEMBL6773214 | 0.82 | EPHX1 (0.44) | EPHX1KDM4EALDH1A1GAA | |
| SCHEMBL6773171 | 0.82 | TSHR (0.38) | KDM4EALDH1A1GAAHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |