SCHEMBL18969717

SCHEMBL18969717

Cc1ccc(OC(=O)CC(=O)Oc2ccc(C(C)(C)c3ccc(OC(=O)CC(=O)Oc4ccc(C(C)(C)c5ccc(OC(=O)CC(=O)Oc6ccc(C)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
HSD17B10 Q99714 1/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 1/20 0.45
MEN1 O00255 2/20 0.43
MMP13 P45452 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12722242 0.95 LMNA (0.50) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL677362 0.92 LMNA (0.47) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL241601 0.87 LMNA (0.61) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL15763957 0.85 KIF11 (0.50) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL2703212 0.84 ALDH1A1 (0.47) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL15827154 0.84 LMNA (0.53) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL13633980 0.83 KMT2A (0.51) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL18295376 0.83 LMNA (0.49) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL410353 0.83 LMNA (0.48) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL12300578 0.82 LMNA (0.74) LMNAGAAKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170166513-A1 EPOXY RESIN CURING AGENT AND PREPARATION METHODS AND USES THEREOF GUANGDONG GUANGSHAN NEW MATERIALS CO., LTD. (CN) 2017-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166513-A1 EPOXY RESIN CURING AGENT AND PREPARATION METHODS AND USES THEREOF EPHX1, EPHX2, EED LMNA 773/4885GAA 2063/4885KMT2A 592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.