Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783053 | 0.88 | KDM4E (0.44) | ALDH1A1SMN1; SMN2LMNATLR7TLR8 | |
| SCHEMBL6773457 | 0.85 | L3MBTL1 (0.42) | ALDH1A1TLR7TLR8NUDT1KDM4E | |
| SCHEMBL6768386 | 0.84 | TLR7 (0.42) | ALDH1A1TLR7TLR8NUDT1 | |
| SCHEMBL6287381 | 0.83 | KMT2A (0.44) | NPC1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6097194 | 0.82 | NPY1R (0.45) | SMN1; SMN2LMNATLR7TLR8NUDT1 | |
| SCHEMBL6897348 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TLR7TLR8NUDT1KDM4E | |
| SCHEMBL6777299 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL6773368 | 0.82 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6778932 | 0.82 | ALDH1A1 (0.41) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6279887 | 0.79 | TLR7 (0.41) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |