Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768386 | 0.92 | TLR7 (0.42) | ALDH1A1TLR7TLR8NUDT1 | |
| SCHEMBL6773457 | 0.91 | L3MBTL1 (0.42) | ALDH1A1TLR7TLR8NUDT1KDM4E | |
| SCHEMBL6773368 | 0.87 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6777299 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TLR7TLR8NUDT1KDM4E | |
| SCHEMBL6097194 | 0.84 | NPY1R (0.45) | TLR7TLR8NUDT1KDM4E | |
| SCHEMBL6279887 | 0.84 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6095134 | 0.84 | HRH3 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6701295 | 0.84 | HRH3 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6773193 | 0.84 | GNAI3 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6774583 | 0.83 | MEN1 (0.47) | ALDH1A1TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |