Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650942 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL607460 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL7846935 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL7837815 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL18838590 | 0.69 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL2244402 | 0.67 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL2246651 | 0.67 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| Ether SCHEMBL31356991 | 0.65 | — | — | |
| SCHEMBL10895013 | 0.62 | ACLY (0.48) | ALDH1A1TSHR | |
| SCHEMBL7650268 | 0.62 | ACLY (0.48) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706899-B2 | TETRAHYDRO-3-HYDROXY-5-OXO-2,3-FURANDICARBOXYLIC ACID (GARCINIA ACID) DERIVATIVES MADE BY REFLUXING GARCINIA ACID WITH ALCOHOLS USING AN ACID CATALYST; PHARMACEUTICAL APPLICATIONS | DEPARTMENT OF SCIENCE AND TECHNOLOGY, TECHNOLOGY BHAVAN (IN) | 2004-03-16 | — | — | US | claimed |
| US-20020042528-A1 | Novel acyclic chiral compound from garcinia acid and process for preparing the same | DEPARTMENT OF SCIENCE AND TECHNOLOGY, TECHNOLOGY BHAVAN (IN) | 2002-04-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042528-A1 | Novel acyclic chiral compound from garcinia acid and process for preparing the same | GK, ADH1A, CNR1 | ALDH1A1 166/4885TSHR 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.