Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385667 | 0.87 | — | — | |
| SCHEMBL18103501 | 0.82 | DNM1 (0.41) | TSHRPLA2G2CALDH1A1CYP3A4EPHX1 | |
| SCHEMBL386484 | 0.81 | ALDH1A1 (0.31) | TSHRALDH1A1CYP3A4EPHX1DNM1 | |
| SCHEMBL384488 | 0.80 | — | — | |
| SCHEMBL23058658 | 0.77 | DNM1 (0.38) | TSHRPLA2G2CALDH1A1CYP3A4EPHX1 | |
| SCHEMBL14183047 | 0.77 | DNM1 (0.38) | TSHRPLA2G2CALDH1A1CYP3A4EPHX1 | |
| SCHEMBL13478425 | 0.77 | DNM1 (0.43) | TSHRPLA2G2CALDH1A1CYP3A4EPHX1 | |
| SCHEMBL14113752 | 0.77 | DNM1 (0.38) | TSHRPLA2G2CALDH1A1CYP3A4EPHX1 | |
| SCHEMBL24093451 | 0.77 | TSHR (0.54) | TSHRALDH1A1CYP3A4EPHX1DNM1 | |
| SCHEMBL387580 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |