Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.50 |
| ▸ | MPI | P34949 | 2/20 | 0.46 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | PMM2 | O15305 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYBB | P04839 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775054 | 0.87 | MPI (0.47) | METAP2MPIPHOSPHO1 | |
| SCHEMBL6774242 | 0.87 | MPI (0.47) | METAP2MPIPHOSPHO1 | |
| SCHEMBL6775679 | 0.86 | METAP2 (0.45) | METAP2MPIPHOSPHO1 | |
| SCHEMBL6770431 | 0.86 | METAP2 (0.37) | METAP2MPIPHOSPHO1KDM4EMEN1 | |
| SCHEMBL6781694 | 0.86 | METAP2 (0.42) | METAP2MPIPHOSPHO1 | |
| SCHEMBL6774003 | 0.86 | METAP2 (0.45) | METAP2MPIPHOSPHO1 | |
| SCHEMBL6776356 | 0.85 | MEN1 (0.38) | METAP2MPIPHOSPHO1MEN1ALDH1A1 | |
| SCHEMBL6784087 | 0.84 | METAP2 (0.49) | METAP2 | |
| SCHEMBL6770269 | 0.82 | METAP2 (0.50) | METAP2MPIPHOSPHO1KDM4EMEN1 | |
| SCHEMBL6774757 | 0.82 | TDP1 (0.36) | ALDH1A1CYP3A4CYP2D6MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815459-B2 | USE IN PREVENTING VARIOUS MEDICAL DYSFUNCTIONS AND DISEASES ARISING FROM REACTIVE OXYGEN SPECIES, IN PARTICULAR STROKE, PARKINSON'S DISEASE, ALZHEIMER'S DISEASE; LIPID PEROXIDATION INHIBITION ACTIVITY | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-11-09 | — | — | US | disclosed |
| US-20030220337-A1 | Seleno compounds containing nitrone moiety, their preparation and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2003-11-27 | — | — | US | disclosed |
| WO-2003010154-A1 | SELENO COMPOUNDS CONTAINING NITRONE MOIETY, THEIR PREPARATION AND THEIR THERAPEUTIC USES | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220337-A1 | Seleno compounds containing nitrone moiety, their preparation and their therapeutic uses | GPX4, GPX1, LPO | METAP2 3428/4885MPI 3025/4885PHOSPHO1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.