SCHEMBL677424

SCHEMBL677424

Cc1cc(Cc2cc(C)c(C)c(C)c2)c(O)c(Cc2cc(C)cc(Cc3cc(C)c(C)c(C)c3)c2O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.53
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
HIF1A Q16665 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HSPA5 P11021 2/20 0.48
CYP2D6 P10635 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SHBG P04278 1/20 0.46
HMGB1 P09429 1/20 0.39
CXCL12 P48061 1/20 0.39
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
GAA P10253 2/20 0.36
SELL P14151 1/20 0.34
SELP P16109 1/20 0.34
SELE P16581 1/20 0.34
ACHE P22303 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20717779 0.94 SHBG (0.48) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL14753784 0.90 SHBG (0.53) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1269461 0.90 AMY1A (0.55) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30374768 0.90 AMY1A (0.55) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL2754938 0.88 SHBG (0.53) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL13038078 0.86 CYP2C9 (0.47) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL13126285 0.85 AMY1A (0.55) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4361837 0.85 AMY1A (0.55) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL2754949 0.84 SHBG (0.60) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL20762297 0.84 SHBG (0.50) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053533-B2 Phenolic OH-containing polyimide silicone, epoxy resin and curing agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-11-08 US disclosed
US-8053533-B2 Phenolic OH-containing polyimide silicone, epoxy resin and curing agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-11-08 US disclosed
EP-2033984-B1 Heat-curable polyimide silicone composition and a cured film therefrom SHINETSU CHEMICAL CO (JP) 2011-01-19 EP disclosed
US-7834100-B2 Phenolic OH and radically polymerizable group containing polyimide silicone and epoxy resin SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-16 US disclosed
US-7834100-B2 Phenolic OH and radically polymerizable group containing polyimide silicone and epoxy resin SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-16 US disclosed
US-7781541-B2 Polyimide silicone resin and thermosetting composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-24 US disclosed
US-7781541-B2 Polyimide silicone resin and thermosetting composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-24 US disclosed
US-20100119744-A1 OPHTHALMIC LENS, CULTURE SUBSTRATE MATERIAL FOR CELL OR ORGAN, CONTAINER FOR LIVING THING AND TRANSPARENT GEL OBTAINED BY POLYMERIZATION OF CYCLIC SILOXANE AND THEIR PRODUCTION METHOD MENICON CO., LTD. (JP) 2010-05-13 US disclosed
US-20100119744-A1 OPHTHALMIC LENS, CULTURE SUBSTRATE MATERIAL FOR CELL OR ORGAN, CONTAINER FOR LIVING THING AND TRANSPARENT GEL OBTAINED BY POLYMERIZATION OF CYCLIC SILOXANE AND THEIR PRODUCTION METHOD MENICON CO., LTD. (JP) 2010-05-13 US disclosed
US-20100056730-A1 SOLVENT-FREE POLYIMIDE SILICONE RESIN COMPOSITION AND CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-03-04 US disclosed
US-20090062479-A1 Heat-curable polyimide silicone Composition and a cured film therefrom SHIN-ETSU CHEMICAL CO., LTD. 2009-03-05 US disclosed
US-20090062479-A1 Heat-curable polyimide silicone Composition and a cured film therefrom SHIN-ETSU CHEMICAL CO., LTD. 2009-03-05 US disclosed
US-7432313-B2 Solvent-free polymide silicone resin composition and a cured resin film thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-10-07 US disclosed
US-7432313-B2 Solvent-free polymide silicone resin composition and a cured resin film thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-10-07 US disclosed
US-7405244-B2 Solvent-free polyimide silicone resin composition and a resin film composed of the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-07-29 US disclosed
US-7405244-B2 Solvent-free polyimide silicone resin composition and a resin film composed of the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-07-29 US disclosed
EP-1902737-A1 OPHTHALMIC LENS, CELL OR ORGAN CULTURE SUBSTRATE, CONTAINER FOR BIOLOGICAL MATERIAL AND TRANSPARENT GEL PRODUCED BY POLYMERIZATION OF CYCLIC SILOXANE COMPOUND AND PROCESS FOR PRODUCTION THEREOF MENICON CO., LTD. (JP) 2008-03-26 EP disclosed
EP-1634907-B1 Solvent-free polymide silicone resin composition and a cured resin film thereof SHINETSU CHEMICAL CO (JP) 2008-03-26 EP disclosed
US-20070197680-A1 Polyimide silicone resin and thermosetting composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-23 US disclosed
US-20070197680-A1 Polyimide silicone resin and thermosetting composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-23 US disclosed