Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774495 | 0.91 | TLR7 (0.43) | TLR7TLR8MCHR1NUDT1 | |
| SCHEMBL6768556 | 0.90 | SMN1; SMN2 (0.49) | TLR7TLR8MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6778937 | 0.89 | TLR7 (0.42) | TLR7TLR8MAPTNUDT1 | |
| SCHEMBL6773275 | 0.88 | TRPV1 (0.43) | TRPV1TLR7HDAC3HDAC1HDAC2 | |
| SCHEMBL6773544 | 0.87 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL6768551 | 0.85 | TLR7 (0.42) | TRPV1TLR7TLR8HDAC3HDAC1 | |
| SCHEMBL6772850 | 0.85 | TLR7 (0.44) | TLR7TLR8HDAC3HDAC1HDAC2 | |
| SCHEMBL6775222 | 0.85 | TLR7 (0.46) | TLR7TLR8HDAC3HDAC1HPGD | |
| SCHEMBL6772811 | 0.84 | ALDH1A1 (0.46) | TLR7TLR8HDAC3HDAC1HDAC2 | |
| SCHEMBL6772805 | 0.84 | TRPV1 (0.44) | TRPV1TLR7TLR8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |