Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768615 | 0.91 | TLR7 (0.39) | HDAC3HDAC1TLR8TLR7MCHR1 | |
| SCHEMBL6772889 | 0.90 | SMN1; SMN2 (0.48) | HDAC3HDAC1NPC1RAB9AHPGD | |
| SCHEMBL6772832 | 0.89 | TP53 (0.47) | HDAC3HDAC1BRD4HDAC2TLR8 | |
| SCHEMBL6779395 | 0.88 | TLR7 (0.46) | HDAC3HDAC1HDAC2TLR8TLR7 | |
| SCHEMBL6778818 | 0.86 | HDAC3 (0.47) | HDAC3HDAC1HDAC2TLR8TLR7 | |
| SCHEMBL6778546 | 0.85 | ALDH1A1 (0.45) | HDAC3HDAC1HDAC2TLR8TLR7 | |
| SCHEMBL6777494 | 0.85 | DRD2 (0.39) | TLR7ALDH1A1 | |
| SCHEMBL6768551 | 0.84 | TLR7 (0.42) | TRPV1HDAC3HDAC1BRD4HDAC2 | |
| SCHEMBL6774530 | 0.84 | TRPV1 (0.42) | TRPV1HDAC3HDAC1HDAC2GCGR | |
| SCHEMBL6771963 | 0.83 | MAPT (0.46) | NPC1RAB9AMCHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |