Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774495 | 0.91 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6773386 | 0.88 | TP53BP1 (0.49) | ALDH1A1POLBTP53BP1TLR7EGFR | |
| SCHEMBL6773544 | 0.87 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL6773863 | 0.87 | GAA (0.47) | ALDH1A1TLR7TLR8NAMPTMAPT | |
| SCHEMBL6772917 | 0.86 | TLR7 (0.45) | ALDH1A1POLBTP53BP1TLR7TLR8 | |
| SCHEMBL6768596 | 0.86 | MCHR1 (0.47) | TLR7TLR8HDAC3NAMPT | |
| SCHEMBL6772850 | 0.85 | TLR7 (0.44) | TLR7TLR8HDAC3HDAC1HDAC2 | |
| SCHEMBL6778546 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBTP53BP1TLR7TLR8 | |
| SCHEMBL6778937 | 0.84 | TLR7 (0.42) | POLBTLR7TLR8MAPTNUDT1 | |
| SCHEMBL6774530 | 0.84 | TRPV1 (0.42) | TLR7TLR8HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |