Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.53 |
| ▸ | MMP9 | P14780 | 14/20 | 0.53 |
| ▸ | MMP3 | P08254 | 12/20 | 0.53 |
| ▸ | MMP13 | P45452 | 12/20 | 0.53 |
| ▸ | MMP1 | P03956 | 11/20 | 0.53 |
| ▸ | MMP7 | P09237 | 10/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769905 | 0.91 | MMP2 (0.53) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6768565 | 0.89 | MMP2 (0.53) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6779702 | 0.89 | MMP2 (0.52) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL5635765 | 0.82 | MMP2 (0.62) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6768748 | 0.79 | MMP2 (0.57) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7945709 | 0.78 | MMP2 (0.54) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL14191410 | 0.77 | RECQL (0.63) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL14191408 | 0.75 | MMP2 (0.74) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6772209 | 0.70 | ADAMTS4 (0.53) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL15943338 | 0.69 | MMP2 (0.75) | MMP2MMP9MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762198-B2 | SUCH AS 2-((4'-METHOXY-(1,1'-BIPHENYL)-4-YL)-SULFONYL)-AMINO-3-(2-PHENOXYMETHYL -(1,3)DIOXAN-2-YL)PROPIONIC ACID | THE PROCTER & GAMBLE COMPANY | 2004-07-13 | — | — | US | disclosed |
| US-6566381-B1 | For therapy of arthritis, cancer, cardiovascular disorder, skin disorder, ocular disorder, inflammation and gum disease | THE PROCTER & GAMBLE COMPANY | 2003-05-20 | — | — | US | disclosed |
| EP-1165530-A2 | DIHETERO-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051993-A2 | DIHETERO-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |