Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775591 | 1.00 | FNTA (0.49) | FNTAFNTBCYP11B1CYP11B2CYP1A2 | |
| SCHEMBL3515844 | 0.80 | NR4A2 (0.57) | CYP11B1CYP11B2MAPK1CFTRSLC2A1 | |
| SCHEMBL6776132 | 0.78 | ALDH1A1 (0.48) | CYP1A2LMNACYP2C19HSD17B10GABRA1 | |
| SCHEMBL6777550 | 0.78 | FNTA (0.72) | FNTAFNTB | |
| SCHEMBL6776943 | 0.77 | FNTA (0.55) | FNTAFNTB | |
| SCHEMBL3517564 | 0.76 | CYP11B1 (0.55) | CYP11B1CYP11B2HSD17B10MAPK1CFTR | |
| SCHEMBL22887482 | 0.76 | ALDH1A1 (0.62) | CYP11B1CYP11B2CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL29496403 | 0.76 | ALDH1A1 (0.62) | CYP11B1CYP11B2CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL20118979 | 0.76 | CYP46A1 (0.56) | CYP11B1CYP11B2LMNAHSD17B10MAPK1 | |
| SCHEMBL7604169 | 0.76 | FNTA (0.84) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693123-B2 | (4-(3-PYRIDYLAMINOMETHYLENE)-2-PHENYLBENZOYL)-N -METHYLMETHIONINE, METHYL ESTER FOR EXAMPLE; RESTENOSIS, HYPERPLASIA | UNIVERSITY OF PITTSBURGH | 2004-02-17 | — | — | US | disclosed |