Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937244 | 0.90 | ESR1 (0.47) | ESR1ESR2TSHRLMNATYR | |
| SCHEMBL16684959 | 0.80 | ESR1 (0.40) | ESR1ESR2TSHRLMNATYR | |
| SCHEMBL11564596 | 0.80 | HRH3 (0.44) | ESR1ESR2TSHRLMNATYR | |
| SCHEMBL11301676 | 0.78 | ESR1 (0.55) | ESR1ESR2TSHRLMNATYR | |
| SCHEMBL11437777 | 0.78 | SHBG (0.55) | ESR1ESR2TSHRLMNATYR | |
| SCHEMBL10907259 | 0.78 | ESR1 (0.39) | ESR1ESR2TSHRLMNATYR | |
| SCHEMBL5459169 | 0.78 | ESR1 (0.48) | ESR1ESR2TSHRLMNATYR | |
| SCHEMBL6140283 | 0.77 | KIF11 (0.37) | TSHRCYP3A4HPGDALDH1A1KIF11 | |
| SCHEMBL7740564 | 0.76 | TSHR (0.55) | TSHRCYP3A4ALDH1A1KDM4EMEN1 | |
| SCHEMBL239232 | 0.75 | ESR1 (0.50) | ESR1ESR2TSHRLMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110062424-A1 | POLYMER COMPOSITIONS COMPRISING ADDITIVE BLOCK COPOLYMERS | NITTO DENKO CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |