Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704505 | 0.81 | ESR1 (0.65) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL8517865 | 0.79 | ALDH1A1 (0.37) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL5459169 | 0.76 | ESR1 (0.48) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL11437777 | 0.76 | SHBG (0.55) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL677567 | 0.75 | ESR1 (0.52) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL11567344 | 0.74 | ESR1 (0.56) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL11564596 | 0.74 | HRH3 (0.44) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL16684959 | 0.74 | ESR1 (0.40) | ESR1ESR2CYP3A4TSHRLMNA | |
| SCHEMBL11297263 | 0.73 | KEAP1 (0.42) | ESR1ESR2CYP3A4TSHRALDH1A1 | |
| SCHEMBL10907259 | 0.72 | ESR1 (0.39) | ESR1ESR2CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512333-B2 | Phosphoric acid resistant polymaleimide prepolymer compositions | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2016-12-06 | — | — | US | disclosed |
| EP-2417168-B1 | PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS | HUNTSMAN ADV MAT AMERICAS INC (US) | 2014-11-26 | — | — | EP | disclosed |
| US-20130231021-A1 | Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2013-09-05 | — | — | US | disclosed |
| US-8445699-B2 | Phosphoric acid resistant polymaleimide prepolymer compositions | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2013-05-21 | — | — | US | disclosed |
| EP-2417168-A1 | PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS | Huntsman Advanced Materials Americas LLC (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20120003892-A1 | Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions | Huntsman Advanced Materials Americans LLC (US) | 2012-01-05 | — | — | US | disclosed |
| EP-2271215-A1 | STORAGE-STABLE POLYMALEIMIDE PREPOLYMER COMPOSITIONS | Huntsman Advanced Materials Americas LLC (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010107750-A1 | PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2010-09-23 | — | — | WO | disclosed |
| WO-2009123876-A1 | STORAGE-STABLE POLYMALEIMIDE PREPOLYMER COMPOSITIONS | HUNTSMAN ADVANCED MATERIALS AMERICAS INC. (US) | 2009-10-08 | — | — | WO | disclosed |