Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776784 | 0.94 | ALDH1A1 (0.48) | FAAHEPHX1ALDH1A1HTTKDM4E | |
| SCHEMBL6783335 | 0.89 | CCR3 (0.46) | FAAHHTTKDM4EMAPTLMNA | |
| SCHEMBL6778478 | 0.88 | HDAC3 (0.48) | FAAHHTTKDM4EMAPTLMNA | |
| SCHEMBL6779314 | 0.88 | QPCT (0.45) | FAAHALDH1A1MAPTLMNAPOLB | |
| SCHEMBL6778012 | 0.87 | CCR3 (0.45) | FAAHALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6778719 | 0.87 | KMT2A (0.48) | ALDH1A1HTTMAPTLMNARAB9A | |
| SCHEMBL6776742 | 0.86 | CCR3 (0.48) | RAB9ASMN1; SMN2CCR3 | |
| SCHEMBL6776452 | 0.86 | TLR7 (0.46) | FAAHEPHX1ALDH1A1HTTMAPT | |
| SCHEMBL6777351 | 0.85 | CA12 (0.41) | FAAHALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6095386 | 0.85 | TLR7 (0.50) | FAAHEPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |