Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 13/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781852 | 0.88 | CCR3 (0.42) | CCR3TLR7HTR2ANPC1RAB9A | |
| SCHEMBL6776742 | 0.88 | CCR3 (0.48) | CCR3HTR2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6776452 | 0.88 | TLR7 (0.46) | TLR7TLR8MAPT | |
| SCHEMBL6768596 | 0.88 | MCHR1 (0.47) | TLR7TLR8 | |
| SCHEMBL6777586 | 0.88 | PKM (0.47) | CCR3TLR7HTR2ANPC1RAB9A | |
| SCHEMBL6773021 | 0.87 | CCR3 (0.41) | CCR3TLR7TLR8SMN1; SMN2MAPT | |
| SCHEMBL6782531 | 0.86 | CCR3 (0.42) | CCR3TLR7TLR8HTR2ANPC1 | |
| SCHEMBL6782943 | 0.85 | CCR3 (0.43) | CCR3TLR7TLR8HTR2ANPC1 | |
| SCHEMBL30345279 | 0.84 | TLR8 (0.53) | TLR7TLR8 | |
| SCHEMBL483357 | 0.84 | TLR8 (0.53) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |