Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030293 | 0.95 | TLR7 (0.46) | TLR7TLR8ALDH1A1NUDT1FAAH | |
| SCHEMBL6781852 | 0.90 | CCR3 (0.42) | TLR7MAPT | |
| SCHEMBL6783075 | 0.90 | HDAC3 (0.43) | TLR7TLR8ALDH1A1NUDT1MAPT | |
| SCHEMBL6776337 | 0.89 | TLR8 (0.45) | TLR7TLR8ALDH1A1NUDT1MAPT | |
| SCHEMBL6777586 | 0.89 | PKM (0.47) | TLR7ALDH1A1MAPTHTT | |
| SCHEMBL6782683 | 0.89 | MEN1 (0.44) | TLR7TLR8NUDT1MAPT | |
| SCHEMBL6773021 | 0.89 | CCR3 (0.41) | TLR7TLR8MAPT | |
| SCHEMBL6776089 | 0.88 | CCR3 (0.44) | TLR7TLR8MAPT | |
| SCHEMBL6773544 | 0.87 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL6777836 | 0.86 | TLR7 (0.43) | TLR7TLR8ALDH1A1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |