Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775222 | 0.90 | TLR7 (0.46) | ADORA2ATLR7TLR8GAANAMPT | |
| SCHEMBL6773863 | 0.89 | GAA (0.47) | MCHR1TLR7TLR8GAANAMPT | |
| SCHEMBL6773077 | 0.88 | MCHR1 (0.49) | MCHR1ADORA2ACCR5GAANAMPT | |
| SCHEMBL6776089 | 0.88 | CCR3 (0.44) | TLR7TLR8 | |
| SCHEMBL6773544 | 0.87 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL6779968 | 0.86 | MCHR1 (0.47) | MCHR1ADORA2ATLR7TLR8CCR5 | |
| SCHEMBL6772811 | 0.86 | ALDH1A1 (0.46) | TLR7TLR8NAMPTHDAC3 | |
| SCHEMBL6772850 | 0.85 | TLR7 (0.44) | TLR7TLR8HDAC3 | |
| SCHEMBL6780382 | 0.83 | TLR7 (0.44) | TLR7TLR8 | |
| SCHEMBL1312806 | 0.83 | TLR7 (0.51) | TLR7TLR8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |