Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776249 | 0.91 | QPCT (0.47) | TLR8QPCTKMT2AALDH1A1GAA | |
| SCHEMBL6776452 | 0.89 | TLR7 (0.46) | TLR8TLR7NUDT1ALDH1A1MAPT | |
| SCHEMBL6779314 | 0.86 | QPCT (0.45) | QPCTKMT2AALDH1A1GAAPOLB | |
| SCHEMBL6674213 | 0.85 | TLR7 (0.50) | TLR8TLR7KMT2A | |
| SCHEMBL5030293 | 0.85 | TLR7 (0.46) | TLR8TLR7NUDT1KMT2AALDH1A1 | |
| SCHEMBL6778839 | 0.84 | MAPKAPK2 (0.43) | TLR8TLR7NUDT1QPCTGAA | |
| SCHEMBL6771821 | 0.84 | TLR7 (0.47) | TLR8TLR7NUDT1KMT2AALDH1A1 | |
| Water SCHEMBL6094303 | 0.84 | TLR7 (0.49) | TLR8TLR7 | |
| SCHEMBL6773544 | 0.84 | TLR7 (0.51) | TLR8TLR7NUDT1 | |
| SCHEMBL6779064 | 0.82 | TLR8 (0.40) | TLR8TLR7NUDT1QPCTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |