Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 9/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776337 | 0.91 | TLR8 (0.45) | QPCTMAPTGAAALDH1A1LMNA | |
| SCHEMBL6776616 | 0.88 | QPCT (0.52) | QPCTMAOBSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6773238 | 0.85 | QPCT (0.46) | QPCTMAOBSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6768556 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL6779782 | 0.83 | QPCT (0.46) | QPCTMAOBSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6777110 | 0.82 | ALDH1A1 (0.47) | QPCTMAOBSMN1; SMN2MAPTGAA | |
| SCHEMBL6778932 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2MAPTMAPK1GAAALDH1A1 | |
| SCHEMBL6777586 | 0.80 | PKM (0.47) | MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL6774343 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1LMNAKMT2ATLR8 | |
| SCHEMBL6776452 | 0.80 | TLR7 (0.46) | MAPTALDH1A1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |