Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779782 | 0.91 | QPCT (0.46) | MAPKAPK2QPCTKMT2AALDH1A1MAPT | |
| SCHEMBL6782472 | 0.90 | FAAH (0.47) | TLR8TLR7NUDT1KMT2AALDH1A1 | |
| SCHEMBL6778065 | 0.89 | RAB9A (0.48) | TLR8TLR7NUDT1ALDH1A1LMNA | |
| SCHEMBL6773630 | 0.87 | TLR8 (0.36) | TLR8TLR7NUDT1QPCTHPGD | |
| SCHEMBL6772921 | 0.84 | TLR7 (0.44) | TLR8TLR7NUDT1KMT2AALDH1A1 | |
| SCHEMBL6779395 | 0.84 | TLR7 (0.46) | TLR8TLR7NUDT1KMT2AALDH1A1 | |
| SCHEMBL6778839 | 0.83 | MAPKAPK2 (0.43) | TLR8TLR7NUDT1MAPKAPK2QPCT | |
| SCHEMBL6776337 | 0.82 | TLR8 (0.45) | TLR8TLR7NUDT1QPCTKMT2A | |
| SCHEMBL6094697 | 0.82 | TLR7 (0.42) | TLR8TLR7LMNASMN1; SMN2HTT | |
| SCHEMBL6096076 | 0.82 | TLR7 (0.45) | TLR8TLR7NUDT1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |