Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891035 | 0.89 | NPC1 (0.41) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30128697 | 0.83 | TYR (0.48) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL30128857 | 0.81 | FBP1 (0.44) | NPC1RAB9AMAOAMAOBALDH1A1 | |
| SCHEMBL14993280 | 0.79 | EGFR (0.42) | APPNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL14993281 | 0.79 | EGFR (0.42) | APPNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL14993283 | 0.79 | EGFR (0.42) | APPNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6771097 | 0.79 | LOXL2 (0.41) | NPC1RAB9AMAPT | |
| SCHEMBL566832 | 0.78 | NPC1 (0.45) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5267615 | 0.76 | ALDH1A1 (0.49) | APPNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30128650 | 0.76 | FBP1 (0.49) | NPC1RAB9ACYP19A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815459-B2 | USE IN PREVENTING VARIOUS MEDICAL DYSFUNCTIONS AND DISEASES ARISING FROM REACTIVE OXYGEN SPECIES, IN PARTICULAR STROKE, PARKINSON'S DISEASE, ALZHEIMER'S DISEASE; LIPID PEROXIDATION INHIBITION ACTIVITY | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-11-09 | — | — | US | disclosed |
| WO-2003010154-A1 | SELENO COMPOUNDS CONTAINING NITRONE MOIETY, THEIR PREPARATION AND THEIR THERAPEUTIC USES | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2003-02-06 | — | — | WO | disclosed |