Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782550 | 0.90 | TLR7 (0.40) | KMT2AHTR2ACCR3MAPTALDH1A1 | |
| SCHEMBL6779814 | 0.90 | FAAH (0.47) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL6782960 | 0.89 | CCR3 (0.39) | KMT2AHSD17B10CCR3MAPTLMNA | |
| SCHEMBL6782531 | 0.88 | CCR3 (0.42) | HTR2ACCR3MAPTNPC1RAB9A | |
| SCHEMBL6768616 | 0.88 | MCHR1 (0.47) | KMT2AHSD17B10CCR3MAPTALDH1A1 | |
| SCHEMBL6779540 | 0.87 | MAPT (0.44) | KMT2AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL6777586 | 0.86 | PKM (0.47) | PKMKMT2AHSD17B10ALOX15HTR2A | |
| SCHEMBL6773645 | 0.83 | HDAC3 (0.44) | CCR3MAPTALDH1A1LMNA | |
| SCHEMBL6776787 | 0.83 | MEN1 (0.42) | KMT2ACCR3MAPT | |
| SCHEMBL6777954 | 0.83 | TLR7 (0.41) | KMT2AHSD17B10MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |