Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636256 | 0.94 | KDM4E (0.34) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6634062 | 0.89 | MEN1 (0.32) | MEN1KMT2ATDP1 | |
| SCHEMBL6637359 | 0.86 | HSD17B10 (0.34) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6643127 | 0.83 | — | — | |
| SCHEMBL12752189 | 0.77 | ALDH1A1 (0.40) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6640101 | 0.77 | GRIN1 (0.33) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6088109 | 0.76 | KMT2A (0.37) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6636876 | 0.75 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL10204282 | 0.75 | KMT2A (0.36) | MEN1KMT2ATDP1 | |
| SCHEMBL6637345 | 0.75 | GAA (0.39) | KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713486-B1 | HIGH ACTIVITY AGAINST WILD-TYPE AND MUTANT HIV-1; LOW TOXICITY | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2004-03-30 | — | — | US | disclosed |