Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574954 | 0.80 | APP (0.52) | APPALDH1A1PTPN1NPC1RAB9A | |
| SCHEMBL3151444 | 0.80 | FFAR1 (0.52) | APPFFAR1GPR183CES2CES1 | |
| SCHEMBL6774688 | 0.78 | NPC1 (0.42) | ALDH1A1GPR183CES2CES1NPC1 | |
| SCHEMBL22905187 | 0.78 | APP (0.53) | APPFFAR1ALDH1A1GPR183CES2 | |
| SCHEMBL21066942 | 0.78 | GPR183 (0.40) | ALDH1A1GPR183CES2CES1CA1 | |
| SCHEMBL8443849 | 0.78 | APP (0.49) | APPFFAR1ALDH1A1GPR183CES2 | |
| SCHEMBL6781061 | 0.78 | VCP (0.52) | FFAR1ALDH1A1CES2CES1GRM5 | |
| SCHEMBL8024378 | 0.78 | CES2 (0.45) | ALDH1A1GPR183CES2CES1PTPN1 | |
| SCHEMBL3696839 | 0.77 | NPSR1 (0.55) | APPFFAR1ALDH1A1GRM5NPC1 | |
| SCHEMBL11493249 | 0.77 | APP (0.47) | APPFFAR1GPR183CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274246-A1 | AMIDE COMPOUND AND USE THEREOF | 成都分迪药业有限公司 | 2023-01-05 | — | — | WO | disclosed |
| US-6767906-B2 | INHIBIT P34CDC2/CYCLIN BCDC13 KINASE AND PROTEIN TYROSINE KINASE PP60C-SRC AND CAN BE USED FOR TREATMENT OF HYPERPROLIFERATIVE DISEASES, FOR EXAMPLE CHEMOTHERAPY OF TUMOURS OR OSTEOPOROSIS. | NOVARTIS AG (CH) | 2004-07-27 | — | — | US | disclosed |